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2004 Print E-mail

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Falsig J, Pörzgen P, Lotharius J, and Leist M. (2004) Specific Modulation of Astrocyte Inflammation by Inhibition of Mixed Lineage Kinases with CEP-1347. J. Immunol., 173: 2762 - 2770.
Department of Neuropathology, University of Zürich
Link 
Vega RB, Harrison BC, Meadows E, Roberts CR, Papst PJ, Olson EN, and McKinsey TA. (2004) Protein Kinases C and D Mediate Agonist-Dependent Cardiac Hypertrophy through Nuclear Export of Histone Deacetylase 5. Mol. Cell. Biol., 24: 8374 - 8385.
University of Texas Southwestern Medical Center and MyogenLink 
Swallow CJ, Partridge EA, Macmillan JC, Tajirian T, DiGuglielmo GM, Hay K, Szweras M, Jahnen-Dechent W, Wrana JL, Redston M, Gallinger S, and Dennis JW. (2004) {alpha}2HS-glycoprotein, an Antagonist of Transforming Growth Factor ß In vivo, Inhibits Intestinal Tumor Progression. Cancer Res., Sep 2004; 64: 6402 - 6409.Mount Sinai Hospital
Link 
Alexander L. Friedman , Richard DeBiasio and Richik N. Ghosh (2004) High Content Screening (HCS) Bioassays Enabled through Application of Grating Illumination Technique to Fluorescence Microscopy. Microscopy and Microanalysis, 10: 1552-1553Cellomics, Inc.Link 
Fredericks ZL, Forte C, Capuano IV, Zhou H, Bos TV, and Carter P. (2004) Identification of potent human anti-IL-1RI antagonist antibodies. Protein Eng. Des. Sel., 17: 95 - 106.AmgenLink 
Xin H, Bernal A, Amato FA, Pinhasov A, Kauffman J, Brenneman DE, Derian CK, Andrade-Gordon P, Plata-Salamán CR, Ilyin SE. (2004) High-throughput siRNA-based functional target validation. J Biomol Screen. Jun;9(4):286-93 .Johnson & Johnson Pharmaceutical Research & Development Link 
Chuma M, Sakamoto M, Yasuda J, Fujii G, Nakanishi K, Tsuchiya A, Ohta T, Asaka M, Hirohashi S. (2004) Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma. J Hepatol. 2004 Oct;41(4):629-36.National Cancer Center Research Institute, Japan 
Koide N. (2004) Automated live-cell and kinetic fluorescence image analysis system--KineticScan HCS Reader. Tanpakushitsu Kakusan Koso. 2004 Aug;49(11 Suppl):1656-7Article in Japanese 
Xua JJ, D Diaz, PJ O’Brien (2004) Applications of cytotoxicity assays and pre-lethal mechanistic assays for assessment of human hepatotoxicity potential. Chemico-Biol. Int 150: 115-128Pfizer, Inc and Cerep 
Chang KH, PW Zandstra (2004) Quantitative Screening of Embryonic Stem Cell Differentiation: Endoderm Formation as a Model. Biotechnol Bioeng. 88:287-98.University of Toronto 
Schlag BD, Z Lou, M Fennell, J Dunlop (2004). Ligand dependency of 5-HT2C receptor internalization. J Pharmacol Exp Ther. 310:865-870.Wyeth Research 
Partridge EA, C Le Roy, GM Di Guglielmo, J Pawling, P Cheung, M Granovsky, IR Nabi, JL Wrana, JW Dennis (2004) Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis. Science 306(5693):120-4Mt Sinai Hospital 
Vakkila J, RA DeMarco, MT Lotze (2004) Imaging analysis of STAT1 and NF-kB translocation in dendritic cells at the single cell level. J Immunol Methods 294:123-134.University of Pittsburgh Molecular Medicine Institute 
Mastyugin V, E McWhinnie, M Labow, F Buxton (2004) A Quantitative High-Throughput Endothelial Call Migration Assay. J. Biomol Screen 9:712-718.Novartis Institutes for Biomedical Research, Cambridge MA 
Vogt A, EN Kalb, JS Lazo (2004) A scalable high-content cytotoxicity assay insensitive
to changes in mitochondrial metabolic activity. Oncol Res.14:305-14.
University of Pittsburgh 
Ghosh RN, L Grove, O Lapets (2004) A Quantitative Cell-Based High-Content Screening Assay for the Eperidermal Growth Factor Receptor-Specific Activiation of Mitogen-Activated Protein Kinase. Assay Drug Dev Tech 2:473-481Cellomics, Inc. 
Richards GR, RM Millard, M Leveridge, J Kerby, PB Simpson (2004). Quantitative Assays of Chemotaxis and Chemokinesis for Human Neural Cells. Assay Drug Dev Tech 2: 465-472.Merck 
Tencza SB and MA Sipe (2004) Detection and Classification of Threat Agents via High-Content Assays of Mammalian Cells. J. Appl. Tox. 24: 371-377.Cellomics, Inc. 
Nam J-S, Y Ino, Y Kanai, M Sakamoto, S Hirohashi (2004) 5-aza-2'-deoxycytidine restores the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis. Clin Exp Metastasis 21:49-56National Cancer Research Institute; Keio University, Japan 
Abraham V, B Samson, O Lapets, JR Haskins (2004) Automated Classification of Individual Cellular Responses Across Multiple Targets. Preclinica 2:349-355.Cellomics, Inc.
Guiliano K, Y-T Chan, DL Taylor (2004) High-Content Screening with siRNA Optimizes a Cell Biological Approach to Drug Discovery: Defining the Roll of p53 Activation in the Cellular Response to Anticancer Drugs. J Biolmol Screening 9:557-568Cellomics, Inc. 
Lovborg, H, P Nygren, and R Larsson. (2004) Multiparametric evaluation of apoptosis: effects of standard cytotoxic agents and the cyanoguanidine CHS 828. Mol. Cancer Ther. 3:521-526Uppsala University 
Bhawe, KM, RA Blake, DO Clary, PM Flanagan. (2004) An Automated Image Capture and Quantitation Approach to Identify Proteins Affecting Tumor Cell Proliferation. J Biomol Screen 9:216-222.Sugen 
Gasparri, F, M Mariani, F Sola and A Galvani. (2004) Quantification of the proliferation index of human dermal fibroblast cultures with the ArrayScan high content screening reader. J Biomol Screen 9:232-243.Nerviano (Pharmacia) Italy 

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