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The most flexible morphology measurement tool available!
Catalog No. S50-0023-1
DescriptionPhysiological processes in cells are often accompanied by changes in cellular morphology. Examples include changes in the intracellular location, arrangement and structure of cellular constituents, such as organelles, macromolecular clusters or the cytoskeleton, changes in the morphology of the entire cell, such as its shape and area, changes in the spacing and proximity between cells, and properties of multi-cellular colonies such as its shape, size and cell locations. The ability to detect subtle changes that are observable by eye in a objective, quantitative manner makes Morphology Explorer a must-have BioApplication for high-content screening. Morphology Explorer provides multiple quantitative measurements over three different dimensional scales: (1) subcellular, (2) whole cell, and (3) inter- or multi-cellular, that give you maximum flexibility to answer a wide range of morphological questions. Its features and capabilities provide you with the power to quantitate a variety of morphological changes, and includes validated Assay Protocols for the following types of assays:
• Colony formation
• Actin and tubulin rearrangement (Figures 1-3)
• Tube formation (Figures 4 and 5)
• Process detection and measurement
• Spot analysis and distribution
• Cell size and spreading
which offer excellent starting points for developing your morphological assays. These protocols, combined with sophisticated object and subpopulation identification methods, make Morphology Explorer a powerful, information-rich method of evaluating compounds and their cell biological effects. Features- Measures subcellular morphology, whole cell morphology, and inter or multi-cellular morphology.
- Reports amount, location, arrangement, and morphology of intracellular objects (such as organelles, compartments or macromolecular clusters).
- Identifies and reports properties of intracellular cytoskeletal fibers such as their number, alignment, arrangement and texture.
- Calculates multiple features related to whole cell morphology such as dimensions, area, shape, and alignment within a field.
- Reports proximity and spacing between like and unlike cells for analyzing mixed cell distribution patterns.
Benefits- Turns observational, qualitative experimentation into quantitative cell biological results.
- Enables screening of difficult to measure targets.
- Automates a usually laborious process, reducing time of analysis from weeks to hours.
Click the link below to view available product brochure 
Click the link below to view available product application note
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