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2008 Print E-mail

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Jeffrey KD, Alejandro EU, Luciani DS, Kalynyak TB, Hu X, Li H, Lin Y, Townsend RR, Polonsky KS, Johnson JD. (2008) Carboxypeptidase E mediates palmitate-induced {beta}-cell ER stress and apoptosis. Proc Natl Acad Sci U S A. Jun 11.Department of Cellular and Physiological Sciences, University of British ColumbiaLink 
Yoshiaki Furukawa, Kumi Kaneko, Koji Yamanaka, Thomas V. O'Halloran, and Nobuyuki Nukina (2008) Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in familial form of ALS. J. Biol. Chem, 10.1074/jbc.M802083200.Laboratory for Structural Neuropathology,RIKEN, Brain Science Institute, Wako, SaitamaLink 
Johnson MC, Damon IK, Karem KL. (2008) A rapid, high-throughput vaccinia virus neutralization assay for testing smallpox vaccine efficacy based on detection of green fluorescent protein. J Virol Methods. Jun;150(1-2):14-20.Division of Viral and Rickettsial Diseases, US Centers for Disease Control and PreventionLink 
Radio NM, Breier JM, Shafer TJ, Mundy WR. (2008) Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening. Toxicol Sci. Jun 6.Neurotoxicology Division. U.S. Environmental Protections AgencyLink 
Barnard R, Barnard A, Salmon G, Liu W, Sreckovic S. (2008) Histamine-induced actin polymerization in human eosinophils: an imaging approach for histamine H4 receptor. Cytometry A. Apr;73(4):299-304.Biomarkers & Translational Biology, PfizerLink 
Rogers GC, Rusan NM, Peifer M, Rogers SL. (2008) A Multi-Component Assembly Pathway Contributes to the Formation of Acentrosomal Microtubule Arrays in Interphase Drosophila cells. Mol Biol Cell. May 7Department of Biology, Lineberger Comprehensive Cancer Center, and Carolina Center for Genome Sciences, University of North Carolina at Chapel HillLink 
Dykens JA, Jamieson JD, Marroquin LD, Nadanaciva S, Xu JJ, Dunn MC, Smith AR, Will Y. (2008) In vitro assessment of mitochondrial dysfunction and cytotoxicity of nefazodone, trazodone, and buspirone. Toxicol Sci. Jun;103(2):335-45.Drug Safety Research and Development, Pfizer, IncLink 
Sarker KP, Kataoka H, Chan A, Netherton SJ, Pot I, Huynh MA, Feng X, Bonni A, Riabowol K, Bonni S. (2008) ING2 as a Novel Mediator of Transforming Growth Factor-{beta}-dependent Responses in Epithelial Cells. J Biol Chem. May 9;283(19):13269-79Southern Alberta Cancer Research Institute, Departments of Biochemistry & Molecular Biology and Oncology, Faculty of Medicine, University of CalgaryLink 
Wang JJ, Zhang SX, Mott R, Chen Y, Knapp RR, Cao W, Ma JX. (2008) Anti-inflammatory Effects of Pigment Epithelium-derived Factor in Diabetic Nephropathy. Am J Physiol Renal Physiol. 294. F1166-1173Cell biology,Endocrinology, University of OklahomaLink 
Jennifer L. Beith, Emilyn U. Alejandro and James D. Johnson (2008) Insulin Stimulates Primary β-Cell Proliferation via Raf-1 Kinase. Endocrinology Vol. 149, No. 5 2251-2260University of British Columbia, Vancouver, British ColumbiaLink 
Janaki Narahari, Aric Morgan, Krishna Vattem, Yvonne Sullivan, Douglas Hughes, Eric Hommema, Greg Kilmer and Brian Webb (2008) Analysis of Signaling Pathways using Antibody Microarrays and RNA Interference. The FASEB Journal;22:645.16Research & Development, Thermo Fisher Scientific, Rockford, IL Link 
Lou J, Stancato L, Lee J, Sutherland JJ. (2008) Prioritizing hits from phenotypic high-content screens. Curr Opin Drug Discov Devel. May;11(3):338-45Eli Lilly & CoLink 
Gareth Williams, Andrew Wood, Emma-Jane Williams, Ying Gao, Mary L. Mercado, Alan Katz, Diane Joseph-McCarthy, Brian Bates, Huai-Ping Ling, Ann Aulabaugh, Joe Zaccardi, Yuhong Xie, Menelas N. Pangalos, Frank S. Walsh, and Patrick Doherty (2008) Ganglioside inhibition of neurite outgrowth requires Nogo receptor function; identification of interaction sites and development of novel antagonists. J. Biol. Chem, 10.1074/jbc.M802067200Wolfson Centre for Age-Related Diseases, Kings College London, LondonLink 
Shao-Yin Wei, Min Li *, Sheng-An Tang, Wan Sun, Bo Xu, Jing-Rong Cui, Wen-Han Lin (2008) Induction of apoptosis accompanying with G1 phase arrest and microtubule disassembly in human hepatoma cells by jaspolide B, a new isomalabaricane-type triterpene. Cancer Letters 262 (2008) 114–122State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, ChinaLink 
Lucy Jean Dawes, Julie Ann Eldred, Ian Kevin Anderson, Matthew Sleeman, John R. Reddan, George Duncan, and Ian Michael Wormstone (2008) TGF{beta}-Induced Contraction Is Not Promoted by Fibronectin-Fibronectin Receptor Interaction, or {alpha}SMA Expression. Invest Ophthalmol Vis Sci. Feb;49School of Biological Sciences, University of East AngliaLink 
Loh SH, Francescut L, Lingor P, Bähr M, Nicotera P. (2008) Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen. Cell Death Differ. Feb;15(2):283-98.MRC Toxicology Unit, University of Leicester, Leicester, UKLink 
Levina V, Marrangoni AM, Demarco R, Gorelik E, Lokshin AE. (2008) Multiple effects of TRAIL in human carcinoma cells: Induction of apoptosis, senescence, proliferation, and cytokine production. Exp Cell Res. Apr 15;314(7):1605-16Department of Medicine and University of Pittsburgh Cancer Institute, University of PittsburghLink 
Partha Basu, Richik N. Ghosh, Linnette E. Grove, Linda Klei, and Aaron Barchowsky (2008) Angiogenic Potential of 3-Nitro-4-Hydroxy Benzene Arsonic Acid (Roxarsone) Environmental Health Perspectives Volume 116, Number 4, April 2008 Department of Chemistry and Biochemistry, Duquesne University, Department of Environmental and Occupational Health, University of Pittsburgh, Thermo Fisher ScientificLink 
Jeffrey Cummings, Cassandra Hodgkinson, Rajesh Odedra, Patrizia Sini, Simon P. Heaton, Kirsten E. Mundt, Tim H. Ward, Robert W. Wilkinson, Jim Growcott, Andrew Hughes and Caroline Dive (2008) Preclinical evaluation of M30 and M65 ELISAs as biomarkers of drug induced tumor cell death and antitumor activity. Molecular Cancer Therapeutics 7, 455-463, March 1Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research, University of Manchester, Cancer and Infection Research Area, AstraZeneca PharmaceuticalsLink 
Andreas Vogt, Peter R. McDonald, Aletheia Tamewitz, Rachel P. Sikorski, Peter Wipf, John J. Skoko, III and John S. Lazo (2008) A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells Molecular Cancer Therapeutics 7, 330-340, February 1Departments of Pharmacology and Chemistry, University of Pittsburgh Drug Discovery Institute and Pittsburgh Molecular Libraries Screening CenterLink 
Brianne S. Raccor, Andreas Vogt, Rachel P. Sikorski, Charitha Madiraju, Raghavan Balachandran, Kia Montgomery, Youseung Shin, Yoshikazu Fukui, Won-Hyuk Jung, Dennis P. Curran, and Billy W. Day (2008) Cell-Based and Biochemical Structure-Activity Analyses of Analogs of the Microtubule Stabilizer Dictyostatin. Mol Pharmacol. Mar;73(3):718-26Departments of Chemistry, Pharmacology, Drug Discovery Institute, and Department of Pharmaceutical Sciences, University of Pittsburgh, PittsburghLink 
Joshua Jianxin Wang, Sarah X Zhang, Robert Mott, Ying Chen, Ryan R Knapp, Wei Cao, and Jian-xing Ma (2008) Anti-inflammatory Effects of Pigment Epithelium-derived Factor in Diabetic Nephropathy. Am J Physiol Renal Physiol. Mar 5University of OklahomaLink 
Matthew A. Trammell, Nicole M. Mahoney, David A. Agard1 and Ronald D. Vale2, (2008) Mob4 plays a role in spindle focusing in Drosophila S2 cells. Journal of Cell Science 121, 1284-1292The Howard Hughes Medical Institute and the Department of Biochemistry and Biophysics, University of CaliforniaLink 
Jennifer L. Beith, Emilyn U. Alejandro, and James D. Johnson (2008) Insulin Stimulates Primary -cell Proliferation via Raf-1 Kinase. Endocrinology, doi:10.1210/en.2007-1557University of British ColumbiaLink 
Emilyn U. Alejandro1 and James D. Johnson2 (2008) Inhibition of Raf-1 Alters Multiple Downstream Pathways to Induce Pancreatic β-Cell Apoptosis. J. Biol. Chem., Vol. 283, Issue 4, 2407-2417, January 25University of British ColumbiaLink
Benfang Ruan, Kevin Pong, Flora Jow, Mark Bowlby, Robert A. Crozier, Danni Liu, Shi Liang, Yi Chen, Mary Lynn Mercado, Xidong Feng, Frann Bennett, David von Schack, Leonard McDonald, Margaret M. Zaleska, Andrew Wood, Peter H. Reinhart, Ronald L. Magolda, Jerauld Skotnicki, Menelas N. Pangalos, Frank E. Koehn, Guy T. Carter, Magid Abou-Gharbia, and Edmund I. Graziani (2008) Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities PNAS. January; vol.105 no.1; pp. 33-38
Wyeth ResearchLink 
Yvonne M.-S. Taya, Wai-Leong Tama, Yen-Sin Anga, Philip M. Gaughwina, Henry Yangb, Weijia Wanga, Rubing Liua, Joshy Georgec, Huck-Hui Nga, Ranjan J. Pererad, Thomas Lufkina, Isidore Rigoutsose,f, Andrew M. Thomsona, Bing Lima,g (2008) MicroRNA-134 Modulates the Differentiation of Mouse Embryonic Stem Cells, Where It Causes Post-Transcriptional Attenuation of Nanog and LRH1. Stem Cells Vol. 26 No. 1 January, pp. 17 -29Genome Institute of Singapore, Singapore, Harvard Medical SchoolLink 

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