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2007 Posters

Title
Authors
PDF
Systematic Discovery of Novel Combination Drugs for Huntington Disease Using HCS AssayH.L. Dong1, L. Kifle1, A.B. Wilson1, J.L. Steiger1, J.E. Staunton1, M.S. Lee1, E. Fossale2, S. Reis2, M.E. Macdonald3, R.E. Pacifici3, C.T. Keith1, X. Jin1
1Discovery, CombinatoRx, Incorporated, Cambridge, MA,2Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA,3CHDI, Inc./MRSSI, Inc. Los Angeles, CA
 
A High Content Transmitted Light Method to Quantify β-galactosidase Activity in Senescent Cells and Multi-mode Imaging Strategy to Quantitate in Cell CultureMarni B. Tierno1, Salony Maniar1, Debby Nickischer2, Paul Johnston1, and Scott Keefer2
1University of Pittsburgh Pittsburgh, PA 2Thermo Fisher Scientific, Pittsburgh PA
 
An HCS Comparison of a Compound Library’s Effects on Synaptic Function in Primary Rat Cortical CulturesRebecca J. Henderson, Debby Nickischer, and Scott R. Keefer
A High Content Screening Approach for Measuring Neuronal FunctionAmy M. Peters, Donna M. Miller, Gang Lin, and Jeffrey R. Haskins
Colocalization Studies on Cytochrome-c with MitochondriaBrent Samson, Oleg Lapets, Jeffery Haskins and Chandrasekaran Vasudevan.
Tolerance to Oxygen Glucose Deprivation in Differentiated Adult Hippocampal Neuronal Stem Cells Obtained from Arctic Ground Squirrels (Spermophilus parryii)K.L. Drew, M.S. Wells1, S.L. Christian, and J.A. Kelleher-Andersson1. Univ. of Alaska Fairbanks, Alaska Basic Neuroscience Program, Fairbanks, AK, 1Neuronascent, Inc., Clarksville, MD
A New Way to Study the PI3-Kinase Signaling Pathway Using the AKT Isoforms 1, 2 and 3.Kay Opperman, in Pierce Previews 11(3):16-18.
New Fluorescent Whole Cell Stains for Effective Cell Identification and Segmentation in Fluorescence Microscopy and High Content Screening AssaysSuk J. Hong, Richik N. Ghosh
Novel, Multiplexed, High Content Screening Cell-Based Assays for Activation of the Transcription Factors HIF-1a, CREB, & FOXO3a Kay Opperman, Janaki Narahari, and Richik N. Ghosh
Evaluation of p53 Induction Using High Content ScreeningAnn F. Hoffman, Shannon M. Hamilton, Krishna M. Vatten, Janaki Narahari, and Richik N. Ghosh
New High Content Screening and Cell-Based Assays for InflammationKay Opperman, and Richik N. Ghosh
A New Panel of High Content Screening Cell-Based Assays for in vitro Cytotoxicity MeasurementsBhaskar Mandavilli, Megan Cuda, Chandrasekaran Vasudevan, Richik N. Ghosh
Simultaneous, Quantitative Monitoring of Cytoskeleton Rearrangement and Morphology Changes in Cells Using High Content AnalysisSuk J. Hong, Richik N. Ghosh
A Novel High Content Screening Assay for Monitoring Cell Proliferation Activity by Multiplexed Measurements of DNA Content, BrdU and Ki67Suk J. Hong, Richik N. Ghosh
Profiling of Multiple Signal Pathway Activities by Multiplexing Antibody and GFP-based Translocation AssaysUlla Henriksen, Kay Opperman, Jacob Fog, Richik N. Ghosh, Frosty Loechel, Morten Praestegaard
New High Content Screening Reagent Kits to Monitor Induction of p53 and its Downstream Targets Krishna M. Vattem, Janaki Narahari, Richik N. Ghosh
New High Content Screening Reagent Kits Enabling Simultaneous Quantitative Monitoring of Cytoskeleton Rearrangement and Cell Morphology Changes

Suk J. Hong, Michael Anhalt, and Richik N.Ghosh

New Reagent Kits for the High Content Analysis of Cell Proliferation Activity using BrdU Incorporation and Ki67 ExpressionSuk J. Hong, Kay Opperman, Richik N. Ghosh
New Transcription Factor Activation Kits for High Content Screening and Cell Based Assays Kay Opperman, Roberta Litavecz, Janaki Narahari, and Richik N. Ghosh
New Dylight™ Fluorescence Dyes for High Content Screening and Fluorescence Cell-Based AssaysRichik N. Ghosh, Krishna M. Vattem, Zakir Murtaza, Mike Stanaitis, Chandrasekaran Vasudevan, Boguslawa R. Dworecki, Pauli Undesser, Surbhi Desai, Matthias Wenzel
Novel High Content Screening Assays for Measuring the Wnt and TGF-beta Signaling PathwaysRoberta Litavecz, Kay Opperman, Richik N. Ghosh
Multiplexing of Antibody and GFP-based Translocation Assays: A Pathway to Better Profiling of Cellular SignallingUlla Henriksen, Kay Opperman, Jacob Fog, Richik N. Ghosh, Frosty Loechel, Morten Praestegaard
New Reagent Kits for High Content Cell-Based Assays for CytotoxicityJeffrey R. Haskins, Bhaskar Mandavilli, Megan Cuda, Chandrasekaran Vasudevan, and Richik N. Ghosh
Kinetic Viability Study of Living Cells Using an Automated High Content PlatformRebecca J. Henderson, Debby Nickischer, and Scott R. Keefer
 
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