Bringing life to cell-based assays!

Revolutionize live-cell high-content screening (HCS) with the Thermo Scientific Cellomics ArrayScan® VTI Live Module

Robust Module for Full Live-Cell HCS

Known for its robust imaging and integrated informatics solution, the Thermo Scientific Cellomics ArrayScan® VTI HCS Reader now offers complete live-cell, quantitative kinetic imaging through the addition of the live-cell module. Scientists now have the ability to not only image live cells, but to keep those cells alive for both short- and long-term experiments in a controlled environment similar to that of a tissue culture incubator.

Highlights

• Optional module that can be installed on a new or existing ArrayScan VTI HCS Reader
• Complete environmental control with full reporting of CO2 and temperature over the defined time course
• Works with all Thermo Scientific Cellomics® BioApplication image analysis modules
• Makes powerful motility and kinetic calculations
• Validated performance

Simple Scheduling and Powerful Calculations

Simple scheduling allows for flexibility of scanning the desired area of a plate along with defining the time course and number of scans. With the VTI Live module installed, the ArrayScan VTI HCS Reader has the ability to calculate kinetic features on any output feature. In addition, motility features track live cells over an extended time course and report features such as persistence, acceleration, and directionality on a cell-by-cell or well-by-well level.

Cell Tracking

The most biologically relevant way to perform live-cell HCS is to track each individual cell over your desired time course. Quantitative measurements can be made on cells that are fully tracked throughout the time course.

Additional Live-Cell Chamber Features

• Sub-second imaging frequency
• Long-term cell viability, comparable to an incubator
• Field-installable for current ArrayScan VTI HCS Readers

Compatible Modules for the ArrayScan VTI HCS Reader

• Thermo Scientific CataLyst Express Robot
• ApoTome® Optical Sectioning Module
• 5x through 40x Objectives
• SlidePort™ Slide Insert

Specifications of ArrayScan VTI Live Module

Temperature Control (Software Controlled)	Ambient to 45ºC. Temperature variation is <0.3ºC over 72 hours. Reported feature at each time point.
CO2 Mixed Gas (Software Controlled)	0-10% Saturation with less than 0.1% variation measured across a plate. Reported feature at each time point.
Relative Humidity	Bubbler feature allows for greater than 90% relative humidity inside live-cell chamber.
External Control Module	12”W x 17”D x 19”H control unit for temperature and CO2 control.

New Software Features!

• Software enhancements enable increased productivity and flexibility
• Built-in data reduction capability allows you to save the well, field, or cell-level features you want
• Remap previously acquired images to different channels for rescanning
• Rescan kinetic time point keeping original time stamp
• Open a variety of image formats (e.g., .tif, .bmp, etc.)
• Enhanced kinetic visualization with kinetic movies created directly from vHCS™:View!

Ordering Information

Catalog number - N01-0014A (110V), N01-0014B (230V)
Contact your Thermo Fisher Scientific representative for pricing information today!

Click the link below to view available product application notes

Kinetic Viability Study Using HeLa Cells with Hoechst and YOYO-1

A Live Cell, Kinetic, High Content Screening Application Interrogating Oxidative Stress in Neuroscreen-1™ Cells